QBIL’s research work made the cover of Medical Physics

In the June issue of Medical Physics, the QBIL paper entitled “3D ultrasound image segmentation using wavelet support vector machines” made the cover of the journal. Medical Physics is an official science journal of the American Association of Physicists in Medicine.

Akbari H, Fei BW (corresponding author). 3D ultrasound image segmentation using wavelet support vector machines, Medical Physics 2012;39:2972-2984. Full Text

To read the June issue of Medical Physics, please visit: http://online.medphys.org/resource/1/mphya6/v39/i6

Dr. Baowei Fei was invited to the NIH Biomedical Imaging Technology (BMIT) Study Section.

Dr. Fei was invited to the NIH Biomedical Imaging Technology (BMIT) Study Section. The BMIT Study Section reviews grant applications involving basic, applied, and pre-clinical aspects of the design and development of medical imaging system technologies, their components, software, and mathematical methods for studies at the cellular, organ, small or large animal, and human scale.

Dr. Baowei Fei was granted a U.S. patent for detecting cardiovascular diseases

Systems and methods for generating images for identifying diseases are provided. In one embodiment, a method comprises receiving a first digital radiography (DR) image of at least a portion of a body of a patient, receiving a second DR image of the at least a portion of a body of a patient, the first DR image being captured at a different energy level than the second DR image, and determining common control point locations for both the first and second DR images. The method further comprises generating an optimized DR image by moving portions of a selected one of the first and second DR images with its associated control points to locations that correspond to similar portions of the other of the first and second DR images, applying deformable transformation to one of the first and second DR images and performing a log subtraction on the first and second DR image to generate a dual-energy digital radiography (DEDR) image. – Dec. 2011

Fei B, Gilkeson R, “Systems and methods for generating images for identifying diseases”, United States Patent , No. 8,073,230 Full Text

Congratulations to Andrew Chi for being admitted to the 2015 Class of the Medical College of Georgia.

On February 4, 2011, Andrew Chi received the admission letter to the 2015 Class from the Medical College of Georgia at Georgia Health Sciences University. Andrew is scheduled to graduate from Emory College in May of 2011 with a Bachelor’s of Science in Chemistry and Bachelor’s of Arts in East Asian Studies.

Dr. Baowei Fei received an Award for a Developmental Research Project from the Emory SPORE in Head and Neck Cancer.

Emory University Winship Cancer Institute (Emory WCI) Head and Neck Cancer Specialized Program of Research Excellence (SPORE) is funded by the NIH/NCI. The overall goal of the Emory WCI HNC SPORE is to improve prevention and treatment of head and neck cancer with emphasis on new discoveries, rapid translation to patients who are suffering, disability and morbidity caused by the disease. In this Developmental Research Project, Dr. Fei will collaborate with Drs. Georgia Chen, Dong Shin, and Ronald Voll and develop molecular imaging technology and photodynamic therapy for treatment of head and neck cancer in animal models.

QBIL’s research Work received the Cum Laude Poster Award at the 2011 SPIE Medical Imaging Conference.

Prostate image segmentation research received the Cum Laude Poster Award at the SPIE Medical Imaging: Visualization, Image-guided Procedures and Modeling Conference in Orlando, Florida on February 14, 2011. The research work was entitled “Automatic 3D segmentation of ultrasound images using atlas registration and statistical texture prior”. Authors contributed to this work include X. Yang, D. Schuster, V. Master, P. Nieh, A. Fenster and B. Fei at Emory University.

Dr. Baowei Fei received a five-year NIH R01 grant on molecular image-directed, 3D ultrasound image guided biopsy.

Prostate cancer affects 1 in 6 men in the USA. Every man over the age of 45 is at risk for prostate cancer. Systematic transrectal ultrasound (TRUS)-guided biopsy is the standard method for a definitive diagnosis of prostate cancer. More than 1.2 million prostate biopsies are performed annually and the medical cost is more than two billion dollars each year. However, this technique has a significant sampling error and is characterized by low sensitivity (39-52%). The current biopsy approach can miss up to 30% of prostate cancers. As a negative biopsy does not preclude the possibility of a missed cancer, both the physicians and patients face challenges in making treatment decisions. Due to the increasing number of younger men with potentially early and curable prostate cancer, this problem must be addressed in order to improve cancer detection rate. This project is to develop a molecular image-directed, 3D ultrasound-guided system for targeted biopsy of the prostate. If completely developed, the multimodality molecular image-guided system will be able to be used not only for biopsy but also for brachytherapy, radiofrequency thermal ablation, cryotherapy, and photodynamic therapy. The research could improve prostate cancer detection by using novel molecular imaging technology and by using a new three-dimensional image-guided biopsy device. The molecular image-guided system can be used not only for improved biopsy of diseases but also for minimally invasive therapy of cancers.

Dr. Baowei Fei’s research is highlighted by Emory Magazine: Double Vision – By Mary J. Loftus

“The combined system can provide opportunities for basic research and can open a new window to studying diseases such as Alzheimer’s, Parkinson’s, drug addiction, cancer, and cardiovascular disease,” says Assistant Professor of Radiology Baowei Fei, a Georgia Cancer Coalition Distinguished Scholar. Dr. Fei’s team is working to develop and improve imaging software for the hybrid system. – Autumn 2010

For more information, please visit: http://www.emory.edu/EMORY_MAGAZINE/2010/autumn/scanner.html

Dr. Baowei Fei’s work on MR/PET is highlighted as a featured innovation at the Office of Technology Transfer (OTT) at Emory University

Magnetic resonance imaging (MR) shows details about the soft tissues of the body, such as every curve and indentation in the brain, while positron emission tomography (PET) records processes, such as how much energy is being used or how much blood is flowing into a region. When these imaging techniques were combined in the same scanner a few years ago, a real challenge since the MRI’s strong magnetic field and the PET’s detector and electronics tend to interfere with each other scientists started thinking about the potential wealth of information that could be provided.

For more information, please visit:
When Two is Better Than One: Perfecting the Combined MR/PET

Dr. Baowei Fei received a Coulter Translational Research Award to develop quantification tools for combined MR/PET

PET (Positron Emission Tomography) provides insight into the metabolic and functional alterations related to pathologic process, and CT (Computed X-Ray Tomography) and MRI (Magnetic Resonance Imaging) reveal anatomical changes due to diseases. The combination of two imaging modalities significantly expands their utility, improving sensitivity and specificity for disease detection and diagnosis. With this grant from the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University Dr. Fei and his team will develop image quantification tools that include image registration, classification, segmentation, and attenuation correction for potential use in combined MR/PET.